Last Updated

May 21, 2026

Mercilon and Evra Patch : When is the Patch More Practical than The Pill?

Written by Editorial Team

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Last Updated: May 21, 2026

Mercilon and Evra Patch : When is the Patch More Practical than The Pill?

Written by Editorial Team

Key Information

Insert your summary here.

Go to FAQ

Book Consultation Whatsapp Us

Are you considering the Mercilon Pill or the Evra Patch as your contraceptive choice? At Dame, we empower you to make an informed decision when it comes to your sexual health. In this article, we will delve into the specifics of both options to help you determine which one suits you best.

In the world of combined hormonal contraceptives, birth control pills dominate the market with a wide variety of brands like Mercilon. Unlike birth control pills, there is only one brand of birth control patch in Singapore โ€“ the Evra contraceptive patch.

Both the pill and the patch offer distinct advantages and considerations, making it essential to understand the similarities and differences between them. Here, we compare the Mercilon pill and the Evra patch, detailing all the information you need to know.

Which is More Effective for Birth Control? The Pill or The Patch?

Mercilon pill and Evra patch both act as combined hormonal contraceptives.They both contain a combination of the hormones estrogen and progestin. Mercilon pill and Evra patch work similarly to prevent pregnancy.

The hormones estrogen and progestin found in Mercilon pill and Evra patch work to reduce the risk of pregnancy by:

  • Preventing ovulation

This means your body does not produce eggs for the sperm to fertilise.

  • Keeping the mucus in the cervix thick

This makes it harder for sperm to move to meet the egg to fertilise it.

  • Keeping the lining of the uterus thin

This makes it difficult for a fertilised egg to continue to develop in the body.

Combined hormonal contraception in the form of a pill like Mercilon or a birth control patch like Evra offer highly effective and reversible contraception.

In terms of effectiveness, studies have shown that the birth control patch is as effective as combination pills.

Find out more about the effectiveness of other birth control methods in Singapore.

Mercilon Pill vs Evra Patch: A Comprehensive Side-By-Side Comparison

Both Mercilon and Evra are equally effective in preventing pregnancy. Here, we help you understand their similarities and differences, highlighting their unique benefits and risks to help you make an informed choice.

Type of Progestin

The type of progestin found in the Mercilon pill is desogestrel while the type of progestin found in the Evra patch is norelgestromin.

Mercilon and Evra Patch - Activity of Progestin Agents Commonly Available in Singapore

The main difference among the different progestins are the side effects that can be associated with specific progestins.

Each progestin has slight variations in its estrogenic, or progestational or androgenic activity.

Mercilon and Evra Patch -Adverse Effects Associated with Type of Hormonal Activity

The type of progestin found in Mercilon pill and Evra patch are similar in activity with Mercilon having a slightly higher progestational activity.

It must be understood that user experience with hormonal contraception varies from women to women. Current research has not concluded if a specific type of progestin is better or safer than the other.

A basic understanding of progestin activity helps to guide the selection of hormonal birth control with regards to concerns relating to the side effects.

Otherwise, there is no difference in contraceptive efficacy among the different progestins found in combined hormonal contraceptives.

Dose of Ethinyl Estradiol

A pill of Mercilon contains 0.02 mg or 20 mcg of ethinyl estradiol. Comparatively, each Evra patch contains 0.6 mg 600 mcg of ethinyl estradiol.

Studies comparing the exposure of the average overall ethinyl estradiol concentration in patch users is 60% higher than in pill users on a 35 mcg daily dose of ethinyl estradiol.

Due to an overall increase in estrogen exposure in the body, there may be a modest increased risk of venous thromboembolism or blood clot for patch users compared with users of combined pills.

In women with BMI of โ‰ฅ30 kg/m2, the patch should not be used due to an increased risk of clotting in this group of women. In addition, Evra may be less effective in women weighing โ‰ฅ90 kg.

If you are at a higher risk of clots or are sensitive to a higher estrogen exposure, Mercilon or other brands of birth control pills may be a better option for consideration. Always consult a healthcare professional to understand which birth control option is the best for you.

Read if estrogen-containing contraceptives are safe for you HERE.

It is also important to note that the peak concentration of ethinyl estradiol concentration in patch users is 25% lower than in oral pill users. The patch delivers a more constant level of hormones in the body compared to the pill. This could possibly result in fewer hormonal related side effects compared to the pill.

Ultimately, user experience differs with patch or the pill. Always share your concerns and health goals with your doctors at Dame, we are here to navigate this journey with you.

Generic vs Brand Name

In Singapore, Mercilon has been approved by the HSA for use since 1991 while the Evra contraceptive patch has been approved by HSA for use since 2003. They remain the only brands available in Singapore, their generic equivalents are not registered with the HSA.

In fact, Evra is the only brand of birth control patch registered with the HSA in Singapore.

You may have come across the brand Ortho Evra, it is essentially the same product as Evra, marketed by the same company under a different brand name in the United States.

In the United States, Ortho Evra has been discontinued due to the availability of generic versions of the birth control patch, namely: Xulane (FDA-approved in 2014) and Zafemy (FDA-approved in 2021).

Which has More Benefits? Mercilon or Evra Patch?

Both the pill and the patch are equally effective as birth control options.

Similar to combined birth control pills, the patch is also likely to provide the same non-contraceptive benefits like reduction in menstrual cramps or pain, acne, risk of ovarian and endometrial cancer.

Potential Benefits Unique to Mercilon

Privacy Issues

Pills can be taken privately. A visible patch could draw unwanted attention

Potential Benefits Unique to Evra Patch

Simply Forgetful?

A new Evra patch is replaced on a weekly basis compared to taking a Mercilon pill on a daily basis. Studies have found that a weekly patch application appears to result in improved adherence to the birth control regime. Being able to adhere to your contraceptive option is important as its effectiveness at preventing pregnancy decreases when used incorrectly.

Hate Pills?

Evra patch is useful if you have difficulty swallowing pills.

Constant Hormonal Exposure

The Evra patch delivers a more constant level of hormones in the body compared to the pill. It could possibly result in fewer hormonal related side effects compared to the pill.

Which has More Risks or Side Effects? Mercilon or Evra Patch?

As with all combined hormonal contraceptives, the side effects experienced by both pill or patch users are generally well-tolerated. These side effects often improve within three to six months of use.

Here we address the common concerns about the risks or side effects with the pill or the patch raised by our women at Dame:

Irregular Bleeding

As with all hormonal birth control, you may experience irregular vaginal bleeding also called โ€œbreakthrough bleedingโ€ or โ€œspottingโ€ between your periods for the first few months of taking the pill or using the patch.

You would need to use sanitary protection, but keep taking your pills or using your patches as usual. Irregular vaginal bleeding usually resolves once your body has adjusted to the pill or the patch. However, if bleeding continues or becomes heavy, speak to your doctor at Dame.

Research suggests that irregular bleeding with patch users is similar to that reported in pill users.

Weight Gain

Weight gain is not a significant side effect for either pill or patch users. Studies have shown that there is no established relationship between combined hormonal contraceptives and weight gain.

Can birth control pills cause cancer? Read about it here.

Mood Disorders

Combined hormonal contraceptives do not have a significant negative impact on mood or worsen existing mood disorders. Both the pill or the patch appears to be safe for women with mood disorders, there are also no restrictions on their use in women with depression.

Potential Risks or Side Effects Unique to Mercilon Pill

Forgetfulness

Missing just one dose of Mercilon can result in a reduction in its effectiveness in preventing pregnancy.

Find out what you need to do if you miss a dose of Mercilon HERE.

Potential Risks or Side Effects Unique to Evra Patch

Possible Skin Reactions

Skin reactions that occur at the patch application site like redness or itchiness were reported by approximately 17% of Evra patch users in the Initial clinical trials.

The risk of this side effect can be minimised by applying the Evra patch on a different body area every week when a new patch is applied.

Increased Risk of Clotting

Although research is limited, there is a possibility of an increased risk of blood clots in patch users compared with pill users. Always discuss your concerns and share your medical history with our doctors at Dame.

Patch Detachment

Normal activities (e.g. bathing or showering, using a sauna or exercising) should not affect how well the patch works. The patch is designed to stay in place during these activities.

It was also found that living in a warm, humid climate like Singapore did not increase the risk of patch detachment. Various studies have also verified that the stickiness of the patch was not adversely affected by a vigorous, athletic lifestyle or swimming.

However, you should check that the patch has not fallen off after doing these activities. 2-3% of birth control patch users required a replacement patch due to patches falling off completely or partially in these studies.

What should I do if the patch falls off? Find out HERE.

Dame Empowers Your Choice

When deciding between Mercilon and the Evra patch, several factors come into play. Your choice should be based on your unique preferences and lifestyle.

Lifestyle and Routine

If you have a consistent daily routine and can reliably take a pill at the same time every day, Mercilon may be a suitable choice.

If you have a busy schedule or you prefer a set-it-and-forget-it approach, the once-weekly Evra patch might be more convenient.

Hormonal Sensitivity

Consider whether you have a history of sensitivity to hormonal fluctuations. If so, the steady hormone release from the Evra patch could be beneficial

Skin Sensitivity

If you have skin sensitivity or allergies, you might want to test a small area with the patch before committing to it.

Ultimately, both Mercilon and Evra are highly effective in preventing pregnancy. The choice between Mercilon and Evra should align with your personal preferences and healthcare needs. Consult with our doctors at Dame to discuss your options, considering your lifestyle and medical history to decide which contraceptive method is best for you.

Mercilon Pill vs. Evra Patch

Summary

The choice between Mercilon and Evra Patch ultimately comes down to your individual needs and preferences. Mercilon and Evra are both combined hormonal contraception, differing mainly in their form – the Mercilon pill or the Evra patch.

Both Mercilon and Evra Patch are highly effective in preventing pregnancy when used correctly. The preference between them mainly depends on your unique lifestyle preferences.

It is important to understand that birth control pills are effective tools for preventing pregnancy, they do not prevent or protect against sexually transmitted infections (STIs). It is recommended to use additional contraception like condoms or other barrier methods if STI protection is also a concern.

At the end of the day, prioritise open communication with your healthcare provider who can provide personalised advice based on your unique circumstances. Begin your journey with Dame today!

Frequently Asked Questions (FAQs)

Q: What is the primary difference between Mercilon and the Evra Patch?

Mercilon is an oral contraceptive pill that you need to take daily. It contains a combination of estrogen and progestin.

The Evra Patch, a transdermal contraceptive patch, provides a continuous release of hormones through the skin when applied once a week. It also contains a combination of estrogen and progestin.

Q: How effective are Mercilon and the Evra Patch in preventing pregnancy?

Both Mercilon and the Evra Patch are highly effective when used correctly. Their effectiveness is estimated to be over 99%. However, individual effectiveness can vary depending on factors like your ability to adhere to the prescribed schedule. It is essential to follow your doctorโ€™s instructions diligently to maximise the effectiveness of the contraceptives.

Q: Do I need a prescription to obtain Mercilon or the Evra Patch?

Yes, in Singapore both Mercilon and the Evra Patch require a prescription from a healthcare provider. It is important to consult with a healthcare professional to determine if either option is suitable for you.

Q: Is it safe to buy birth control pills or birth control patches online?

We do not recommend buying birth control pills or patches online because it can be risky and unsafe.

Online pharmacies may sell counterfeit or expired drugs, which can be dangerous for your health. It is also difficult to verify the authenticity and safety of these medications when purchased online.

Moreover, birth control medications require a prescription from a licensed healthcare provider, and buying them online without a prescription is illegal. Additionally, online purchases may not come with the necessary instructions and warnings regarding dosage and side effects.

If you are considering using birth control medications, we recommend consulting with a licensed healthcare provider who can evaluate your health condition and prescribe the appropriate medication. This will ensure that you are using safe and effective medication.

Begin your journey with Dame today!

Disclaimer: Articles on Dame are for informational purposes only and do not constitute medical advice, diagnosis, or treatment. If you have concerns about your health, please consult a licensed doctor for personalised medical advice.

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